{
  boost,
  lib,
  fetchFromGitHub,
  gnum4,
  gperftools,
  hdf5-cpp,
  libpng,
  protobuf,
  python3,
  scons,
  stdenv,
  zlib,
  enableHdf5 ? true,
  enableLibpng ? true,
  enableTrace ? true,
  enableSystemC ? true,
  enableTcmalloc ? true,
  gem5ISA,
}: let
  version = "22.1.0.0";

  isa = assert lib.assertMsg (lib.elem gem5ISA ["arm" "null" "mips" "power" "x86"])
  "${gem5ISA} is not a valid gem5 target ISA";
    lib.toUpper gem5ISA;

  target = "build/${isa}/gem5.opt";
in
  stdenv.mkDerivation {
    pname = "gem5";
    version = "${gem5ISA}-${version}";

    src = fetchFromGitHub {
      repo = "gem5";
      owner = "gem5";

      rev = "v${version}";
      sha256 = "sha256-Yxag8emR6hf7oX4GAtQi/YYcKrpXicUoQg5+rjKyjc0=";
    };

    buildInputs =
      [zlib]
      ++ lib.optional enableHdf5 hdf5-cpp
      ++ lib.optional enableLibpng libpng
      ++ lib.optional enableTrace boost
      ++ lib.optional enableSystemC protobuf
      ++ lib.optional enableTcmalloc gperftools;

    nativeBuildInputs = [gnum4 scons];

    sconsFlags = [target];

    enableParallelBuilding = true;

    # Without this we get "ValueError: invalid width 0 (must be > 0)"
    COLUMNS = 80;

    postPatch = ''
      patchShebangs util/
    '';

    installPhase = ''
      mkdir -p $out/bin/
      cp ${target} $out/bin/
    '';
  }